Search on: LUTEINIZING HORMONE, BETA SUBUNIT 
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Descriptor English:   Luteinizing Hormone, beta Subunit 
Descriptor Spanish:   Hormona Luteinizante de Subunidad beta 
Descriptor Portuguese:   Hormônio Luteinizante Subunidade beta 
Synonyms English:   LH-beta
Luteinizing Hormone, beta Chain
Luteinizing Hormone, beta Polypeptide Chain
Lutropin-beta
LH beta
Lutropin beta
ICSH, beta Subunit
LH, beta Subunit
Lutropin, beta Subunit  
Tree Number:   D06.472.699.322.576.463.500
D06.472.699.631.525.343.463.500
D12.644.548.691.525.343.463.500
Definition English:   The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility. 
History Note English:   2003; use LUTEINIZING HORMONE, BETA SUBUNIT (NM) 1983-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   37314 
Unique Identifier:   D037101 

Occurrence in VHL:
 

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